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Oncology Overdrive

Aug 31, 2023

In this episode, host Shikha Jain, MD, speaks with Cardinal Health’s Parisa Asgarisabet, PhD and Scott Swain, PhD, MPH about benefits and uses of real-world evidence, the issue of diversity in clinical trials and more.

•    Welcome to another exciting episode of Oncology Overdrive 1:11
•    About Swain 1:26
•    About Asgarisabet 2:45
•    The interview 3:30
•    About Swain and how you ended up at Cardinal Health 3:50
•    About Asgarisabet’s journey and how she ended up at Cardinal Health 5:09
•    What is Cardinal Health and why should people know about the work they are doing? 6:37
•    How is the work Cardinal Health is doing directly applicable to practicing oncologists?  7:30 
•    Jain, Asgarisabet, and Swain on Representation of age, race and ethnicity in real-world evidence (RWE), randomized clinical trial (RCT), and Surveillance, Epidemiology, and End Results (SEER) cancer patient registry data in advanced renal cell carcinoma (aRCC). 10:32
•    How can we scale real world data in a bigger way and make this the standard as opposed to the exception? 14:02 
•    Jain and Swain on diversity, equity, and inclusion in the clinical trials design space 17:57
•    Asgarisabet and Swain on the economic implications of a lack of diversity in clinical trials 19:53
•    Swain and Jain on the importance of community engagement and outreach in achieving diversity of backgrounds in clinical trials 24:42
•    What do you think are the next steps to implement real world data in order to make a larger impact? 27:38
•    Should real world data be used in concert with randomized controlled trials or should this data be used independently? 29:02
•    When we talk about these types of transformation in how we look at diseases and deciding the best plan of action, do you anticipate there being a challenge with insurance companies approving treatments using real world data? 30:27
•    If someone could only listen to the last two minutes of this episode, what would you want them to take away? 35:18
•    How to contact Swain and Asgarisabet 37:57
•    Thanks for listening 39:13

Scott Swain, PhD, MPH is a Director of Regulatory Science and Real-world Evidence with Cardinal Health.

Parisa Asgarisabet, PhD is a Lead statistician in the Real-World Evidence & Insights team at Cardinal Health.

We’d love to hear from you! Send your comments/questions to Dr. Jain at Follow Healio on Twitter and LinkedIn: @HemOncToday and Follow Dr. Jain on Twitter: @ShikhaJainMD. Asgarisabet can be reached via LinkedIn or via email Swain can be reached via LinkedIn or via email

Disclosures:  Jain reports no relevant financial disclosures. Asgarisabet and Swain are employees and shareholders of Cardinal Health.