Aug 31, 2023
In this episode, host Shikha Jain, MD, speaks
with Cardinal Health’s Parisa Asgarisabet, PhD and
Scott Swain, PhD, MPH about benefits and uses of
real-world evidence, the issue of diversity in clinical trials and
more.
• Welcome to another exciting episode of Oncology
Overdrive 1:11
• About Swain 1:26
• About Asgarisabet 2:45
• The interview 3:30
• About Swain and how you ended up at Cardinal Health
3:50
• About Asgarisabet’s journey and how she ended up at
Cardinal Health 5:09
• What is Cardinal Health and why should people know
about the work they are doing? 6:37
• How is the work Cardinal Health is doing directly
applicable to practicing oncologists?
7:30
• Jain, Asgarisabet, and Swain on
Representation of age, race and ethnicity in real-world evidence
(RWE), randomized clinical trial (RCT), and Surveillance,
Epidemiology, and End Results (SEER) cancer patient registry data
in advanced renal cell carcinoma (aRCC).
10:32
• How can we scale real world data in a bigger way and
make this the standard as opposed to the exception?
14:02
• Jain and Swain on diversity, equity, and inclusion
in the clinical trials design space
17:57
• Asgarisabet and Swain on the economic implications
of a lack of diversity in clinical trials
19:53
• Swain and Jain on the importance of community
engagement and outreach in achieving diversity of backgrounds in
clinical trials 24:42
• What do you think are the next steps to implement
real world data in order to make a larger impact?
27:38
• Should real world data be used in concert with
randomized controlled trials or should this data be used
independently? 29:02
• When we talk about these types of transformation in
how we look at diseases and deciding the best plan of action, do
you anticipate there being a challenge with insurance companies
approving treatments using real world data?
30:27
• If someone could only listen to the last two minutes
of this episode, what would you want them to take away?
35:18
• How to contact Swain and Asgarisabet
37:57
• Thanks for listening
39:13
Scott Swain, PhD, MPH is a Director of
Regulatory Science and Real-world Evidence with Cardinal
Health.
Parisa Asgarisabet, PhD is a Lead statistician in
the Real-World Evidence & Insights team at Cardinal Health.
We’d love to hear from you! Send your comments/questions to Dr.
Jain at oncologyoverdrive@healio.com.
Follow Healio on Twitter and LinkedIn: @HemOncToday and https://www.linkedin.com/company/hemonctoday/.
Follow Dr. Jain on Twitter:
@ShikhaJainMD. Asgarisabet can be reached via LinkedIn or via
email parisa.asgarisabet@cardinalhealth.com.
Swain can be reached via LinkedIn or via email scott.swain@cardinalhealth.com.
Disclosures: Jain reports no relevant
financial disclosures. Asgarisabet and Swain are employees and
shareholders of Cardinal Health.